COMPOSITION
Duomeal Tablet: Each tablet contains dried Aluminium Hydroxide Gel BP 250 mg (Al2O3 not less than 47%) and Magnesium Hydroxide Powder BP 400 mg.
Duomeal Suspension:Each 5 ml suspension contains Aluminium Hydroxide compressed gel BP 1750 mg (equivalent to Aluminium oxide 175 mg) & Magnesium Hydroxide BP 200 mg.
INDICATION
Aluminium Hydroxide and Magnesium Hydroxide is indicated for Hyperacidity, peptic ulcer, gastritis, heartburn, sour stomach & dyspepsia.
PHARMACOLOGY
This drug is well-balanced combination of essential non-systemic antacids which excel in efficacy and palatability. These are dependable antacid preparations without acid rebound, constipating or cathertic effects. Both the preparations provide symptomatic relief of hyperacidity associated with heartburn, acid ingestion or sour stomach. Aluminium hydroxide gel, a slow acting antacid and an adsorbent with prolonged effect, has high neutralizing power. Magnesium Hydroxide possesses a slow but sustained acid neutralizing property. Antacids of both tablet and suspension possess adsorbent property. They form a protecting coating over the ulcer surface facilitating its healing; thus protecting the sensitive mucosa of stomach and duodenum from further irritation.
DOSE AND ADMINISTRATION
Tablet: Two tablets 1-3 hours after meal and at bed time or as directed by the physician.
Suspension: 2 tea spoonful 1-3 hours after meal and at bed time or as directed by the physician.
CONTRAINDICATION
This is contraindicated in hypophosphataemia. It is also contraindicated in alkalosis and hypermagnesaemia where abdominal distention may be due to partial or complete intestinal obstruction.
WARNINGS AND PRECAUTION
Antacids reduce the absorption of tetracycline when given concomitantly. These should not be used concomitantly
SIDE EFFECTS
Long term use of any antacid results in alkaluria, which may predispose to nephrolithiasis by forming precipitation of calcium phosphate.
USE IN PREGNANCY & LACTATION
It is advised to avoid antacid preparations in the first trimester of pregnancy.
DRUG INTERACTION
This drug inhibits the absorption of following drugs: Azithromycin, cefpodoxime, ciprofloxacin, isoniazid, rifampicin, norfloxacin, ofloxacin, pivampicillin, tetracyclines, Gabapentin and phenytoin, Itraconazole, ketoconazole, Chloroquine, hydroxychloroquine and Phenothiazines.
STORAGE
Store in a cool & dry place below 30º C. Protect from light and moisture. Keep out of reach of children.
PACKING
Duomeal Tablet: Each box containing 10 x20’s tablets in blister pack.
Duomeal Suspension:Each bottle contains 200 ml Suspension.
