COMPOSITION
Mitigal 2% Cream: Each gm cream contains Miconazole Nitrate BP 20 mg.
PHARMACOLOGY
Miconazole topical cream is a broad-spectrum antimycotic which offers a high antifungal activity against dermatophytes, yeasts and other phyco-Asco and Adelomycetes, with a potent antibacterial activity against Gram-positive bacilli and cocci. Miconazole topical cream proved to be markedly effective in secondary infected mycoses, which under other treatments were resistant or reappeared. Miconazole topical cream does not stain skin or clothes.
INDICATION
Skin and nail infections due to dermatophytes, yeasts and other fungi such as:
- Tinea Capitis, Corporis, manuum, pedis, barbae and cruris
- Tinea unguium or onychomycosis
- Pityriasias versicolor
- Candidiasis of skin and nails
- Stomatitis angularis
- Otitis externa
Since Mitigal (Miconazole Nitrate) has an antibacterial effect on Gram-positive bacteria, it may be used in mycoses secondarily infected with such bacteria.
DOSAGE AND ADMINISTRATION
For skin infections:
Apply some cream to the lesions twice daily and rub it well with finger until it has fully penetrated the skin. All lesions usually disappear after 2 to 5 weeks. Prolong treatment may be required to prevent relapse.
For nail infections:
Clip infected nail as shortly as possible. Once daily apply some cream to the infected nail and rub with your finger, cover nail with a non-perforated occlusive plastic bandage. Also after loosening of the infected nail (from 2-3 weeks onwards) uninterrupted treatment should be continued until the growth of a new nail has set in and definite cure can be observed (usually after seven months or more).
CONTRAINDICATION
None known.
PRECAUTION
Mitigal (Miconazole Nitrate) is for external use only. It should not be taken by mouth. Contact with the eyes should be avoided.
SIDE EFFECTS
Rarely, transient local mild irritation, itching & redness may occur immediately after application.
USE IN PREGNANCY AND LACTATION
Only small amounts of Mitigal (Miconazole Nitrate) are absorbed following local administration. However as with other imidazoles, Mitigal (Miconazole Nitrate) should be used with caution during pregnancy. Mitigal (Miconazole Nitrate) has shown no teratogenic effects but shows foetotoxic effect at high doses. As many drugs are excreted in human milk, caution should be exercised when Mitigal (Miconazole Nitrate) is administered to a nursing woman.
STORAGE
Store at a cool & dry place, protect from light & moisture. Keep out of the reach of children.
PACKING
Mitigal 2% Cream: Tube containing 10 gm Cream.
