Composition
Povibac 5% Ointment: Each gram ointment contains Povidone-Iodine USP 50 mg.
Pharmacology
Povibac contains Povidone-Iodine which is stable chemical complex of polyvinylpyrrolidone and elemental iodine. Povibac (Povidone-Iodine) shows non selective broad spectrum germicidal action against all kind of microbes.
Indication
Povibac (Povidone-Iodine) 5% ointment is indicated as an adjunct to systemic therapy in primary or secondary topical infections, infected surgical incisions, infected decubitus or stasis ulcer, pyodermas, secondarily infected dermatoses, and infected traumatic lesions. Prophylactically can be used to prevent microbial contamination in burns, incisions and other topical lesions; for degerming skin in hyperalimentation and catheter care. The use of Povibac (Povidone-Iodine) 5% ointment for abrasions, minor cuts and wounds may prevent the development of infections and permit wound healing.
Dosage & Administration
Povibac (Povidone-Iodine) 5% Ointment:
For the treatment of infection: Apply once or twice daily or at dressing changes for a maximum of 14 days.
For the prevention of infection: Apply once or twice a week for as long as necessary. The affected skin should be cleaned and dried and can be covered with a dressing or bandage.
Or as directed by the physicians.
Contraindication
Regular use is contraindicated in patients with thyroid disorders (in particular nodular colloid goitre, endemic goitre and Hashimoto’s thyroiditis). Povidone-Iodine is not recommended for regular use in neonates and is contraindicated in very low birth weight infants (below 1500 grams).
Precaution
Special caution is needed when regular applications to skin are made to patients with pre-existing renal insufficiency. Regular use should be avoided in patients on concurrent lithium therapy. This preparation is flammable and caution is advised during surgical procedures involving hot wire cautery or diathermy.
Side Effects
Common side effects of Povidone-Iodine include local skin irritation and sensitivity. The application of Povidone-Iodine to large wounds or severe burns may produce systemic adverse effects such as metabolic acidosis, hypernatremia and impairment of renal function.
Use in Pregnancy & Lactation
Regular use of Povidone-Iodine should be avoided in pregnant or lactating women as absorbed iodine can cross the placental barrier and can be secreted into breast milk. Although no adverse effects have been reported from limited use, caution should be recommended.
Drug Interaction
Absorption of iodine from Povidone-Iodine may interfere with thyroid function tests. Contamination with Povidone-Iodine of several types of tests for the detection of occult blood in feces or blood in urine may produce false positive results.
Storage
Store below 30°C, protect from light and moisture. Keep out of the reach of children.
Packaging
Povibac 5 %Ointment: Each tube contains 25 g Povibac 5% ointment.
