Composition
Each 5 ml Syrup contains 2 mg Salbutamol Sulphate BP.
Pharmacology
Ventosol (Salbutamol) is a synthetic sympathomimetic agent with predominant beta-2 adrenergic activity. Ventosolol (Salbutamol) produces bronchodilatation through stimulation of beta- 2-adrenergic receptors in bronchial smooth muscles, thereby causing relaxation of bronchial muscle fibers. This action is manifested by an improvement in pulmonary function as demonstrated by spirometric measurements.
Indications
Ventosol is indicated as a bronchodilator for use in-
- Asthma
- Chronic Bronchitis
- Emphysema and
- Other conditions associated with airways obstruction.
Dosage & Administration
Children:
2-6 years: 2.5 ml syrup, 3-4 times daily.
6-12 years: 5 ml syrup, 3-4 times daily.
Over 12 years: 5-10 ml syrup, 3-4 times daily (2-4 mg tablet, 3-4 times daily).
Adults: 2-4 mg tablet, 3-4 times daily.
Precautions & Warnings
Ventosol (Salbutamol) should be used with caution in patients with hyperthyroidism, cardiovascular disease, occlusive vascular disorders, hypertension and aneurysms. Hypokalaemia associated with high doses of Salbutamol may result in increased susceptibility to digitalis- induced cardiac arrhythmia. Tachyphylaxis with resistance may occur with prolonged use of high dosage. Care is necessary when treating patients with diabetes mellitus or closed angle glaucoma, and in those receiving antihypertensive therapy.
Side Effects
Salbutamol (Salbutamol) may cause fine tremor of skeletal muscles (particularly the hands), palpitations and muscle cramps. Tachycardia, tenseness, headaches and peripheral vasodilatation have been reported after large doses.
Pregnancy & Lactation
The drug should be used during pregnancy only if the potential benefit justifies the potential risk of the fetus. It is not known whether this drug is excreted in human milk. Because of the potential of tumorigenecity shown for Salbutamol in some animal studies, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Overdose
The symptoms with overdosage are angina, headache, nausea, vomiting, tremor etc. The preferred antidote for overdosage with Salbutamol is a cardio-selective beta-blocking agent but beta-blocking drugs should be used with caution in patients with a history of bronchospasm.
Storage
Store below 30°C, protect from light and moisture. Keep out of reach of children.
Packaging
Each PET bottle contains 100 ml syrup and a measuring cup.
