Composition
Each 5 ml suspension contains Aluminium Oxide 200 mg (equivalent to Aluminium Hydroxide Gel USP), Magnesium Hydroxide 400 mg (equivalent to Magnesium Hydroxide Paste USP) and Simethicone 30 mg (equivalent to Simethicone Emulsion USP).
Pharmacology
Both Aluminium Oxide and Magnesium Hydroxide exert antacid action with prolonged duration and thus possess a sustained acid-neutralizing property. Duomeal Plus possesses an absorbent property, which protects the sensitive mucosa from further irritation. Simethicone is an antiflatulant that lowers surface tension of gas and causes bubbles of gas in GIT to coalesce, aiding their dispersion. Thus it rapidly relieves flatulence and abdominal discomfort due to excess gas.
Indication
This is indicated for symptomatic relief of hyperacidity associated with the peptic ulcer, gastritis, peptic oesophagitis, gastric hyperacidity, heartburn, sour stomach or hiatus hernia. It is effective in the prevention of stress ulceration and GI bleeding. It acts as an antiflatulent to alleviate the symptoms of gas including post operative gas pain. This rapidly relieves acid pain, disperses gastric foam and facilitates eructation of gas and air.
Dosage & Administration
1-2 teaspoonful suspension one hour after meal and at bedtime or as directed by the physician..
Route of Administration
By Mouth
Contraindication
Antacid should not be used in patients who are severely debilitated suffering from kidney failure.
Warning & Precaution It is advised to avoid antacid preparations in the first trimester of pregnancy.
Side Effects
Occasionally diarrhoea or constipation may occur if excessive amount is used.
Use in Pregnancy & Lactation
There is no reliable information from human studies. Therefore, antacid should be used if it is absolutely indicated.
Drug Interaction
Drugs containing Aluminium Hydroxide should not be taken concomitantly with any form of tetracyline, as the absorption of tetracyline may be affected. Aluminium Hydroxide may also reduce the absorption of digoxin
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children
Packing
200 ml Bottle