Helben 30 ml Suspension

Mebendazole 100 mg / 5 ml

COMPOSITION

Each 5 ml (1 Teaspoonful) Contains : Mebendazole USP 100 mg

PHARMACOLOGY

Mebendazole is a synthetic broad-spectrum anthelmintic that is active against most nematodes and some other worms. Mebendazole is principally used in the treatment of intestinal nematode infection. Mebendazole inhibits the formation of the worms’ microtubules and causes the worms’ glucose depletion. After oral administration about 2-10% of oral dose is absorbed from Gl tract and peak plasma concentration occurs within 30 minutes to 7 hours. Mebendazole is highly bound to plasma protein. Elimination half-life is 2.8 to 9 hours.

INDICATION

Helben is highly effective against threadworms (Enterobius) round worms (Ascaris), Whipworms (Tricuris) and hookworms (An cylos toma and Necator is single or in onixed intec tions.

DOSAGE AND ADMINISTRATION

By mouth for Thread worm infections:

5 ml (1 Teaspoonful) as a single dose for Patients  of all ages over 2 years.

For round worm infections: 5 ml (Teaspoonful) twice daily for 3 days,

For whip worm infections: 5 ml (1 Teaspoonful) twice daily for 3 days,

For hook worm infections: 5 ml (1 Teaspoonful) twice daily for 3 days,

CONTRAINDICATION

The drug is contraindicated in Children under 2 years.

PRECAUTION

General: Periodic assessment of organ system functions, including haematopoietic and hepatic, is advisable during prolonged therapy.

Information for Patients: Patients should be informed of the potential risk to the foetus in women taking mebendazole during pregnancy, especially during the first trimester. Patients should also be informed that cleanliness is important to prevent reinfection & transmission of the infection.

SIDE EFFECTS

Abdominal pain & diarrohea may occur in cases of massive infestation and exulsion of worms.

DRUG INTERACTION

None significant.

Advice for Dosage and administration : The Same dosage schedule applies to children over two years and adults. If the patient is not cured three weeks after treatment, a second course of treatment is advised; No special steps such as fasting or purging are required before admimisation of the drug.

USE IN PREGNANCY AND LACTATION

Use in Pregnancy : The use of mebendazole is not recomended in pregnant women.

Use in Lactation : Caution should be exercised when mebendazole is administered during lactaion period.

STORAGE PRECAUTION

Store at a cool & dry place, protect from light & moisture. Keep out of the reach of children.

Keep this and all medicines out of rech of children. To be dispensed only by or on the prescriptions of a Registered physician.

PACKING

Helben Suspension: Bottle containing 30ml Suspension.

Helben 30 ml Suspension
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