Metodex 100ml

Dextromethorphan 10mg / 5 ml


Metodex Syrup: Each 5 ml contains Dextromethorphan Hydrobromide BP 10 mg.


Metodex (Dextromethorphan Hydrobromide BP) Syrup is a safe, effective, non-narcotic antitussive agent. Metodex(Dextromethorphan Hydrobromide BP) is a cough suppressant which has a central action on the cough centre in the medulla. Although structurally related to morphine, Metodex has no analgesic properties and in general it has little sedative activity. Addiction has not been observed after the administration of rather large doses for prolonged period. Metodex is rapidly absorbed from the Gl tract and exerts its effects in 15-30 minutes after oral administration. The duration of action is approximately 3-6 hours with conventional dosage from. Metodex is extensively metabolized in the liver and excreted in the urine as unchanged Dextromethorphan and demethylated metabolites including Dextromethorphan which has some cough suppressant activity. Urinary excretion of parent drug and metabolites accounts for up to 50% of the ingested dose over 24 hour. About 8% of the dose is excreted unchanged in urine over the first 6 hour.


Metodex (Dextromethorphan Hydrobromide BP) is indicated in the treatment of

  • Chronic dry cough/unproductive cough.
  • Acute dry cough which is interferring with normal function or sleep.

Adults: 10-20 mg every 4 hours or 30 mg every 6-8 hours to a usual maximum of 120 mg daily. Children (6-12 years): 5-15 mg every 4-8 hours to a maximum of 60 mg daily. Children (2-6 years): 2.5-5 mg every 4 hours or 7.5 mg every 6-8 hours to a maximum of 30 mg daily.

  • Concomitant use of monoamine oxidase inhibitors. • Liver disease. • In patients with respiratory failure.

Do not use Dextromethorphan to control a cough that is associated with smoking, asthma, or emphysema, or a cough that is productive (produces sputum or phlegm).


Adverse effects with Dextromethorphan are rare, but nausea and dizziness sometimes may occur. The drug produces no analgesia or addiction and little or no CNS depression. Excitation, confusion and respiratory depression may occur after over dosage.


Pregnancy: Adequate and well-controlled studies in human have not been done. Therefore Dextromethorphan should be avoided in the first three months of pregnancy.
Lactation: It is not known whether dextromethorphan passes into breast milk, so nursing mothers should be advised not to take the drug.


No special precautions are required and the dose may be adjusted to individual response.


Store in a cool & dry place. Protect from light and moisture. Keep out of reach of children.


Metodex Syrup: Each PET bottle containing 100 ml syrup.

Metodex 100ml
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