Mucovan Syrup

Mucovan Syrup
Ambroxol Hydrochloride BP 15 mg / 5 ml

Composition
Each 5 ml syrup contains 15 mg Ambroxol Hydrochloride BP.

Pharmacology
Mucovan (Ambroxol) is the active metabolite of bromhexine and it has been proven that this metabolite possesses a greater bronchosecretolytic effect than bromhexine. It improves sputum rheology by hydrating mechanism leading to liquefaction of mucus in the lumen of respiratory tract, thus facilitating expectoration of mucus and reducing dyspnea. It stimulates production of phospholipids of surfactant by alveolar cells, thus contributing to the lowering of superficial tension in the alveoli. It also reduces bronchial hyperactivity. Mucovan (Ambroxol) has anti-inflammatory properties owing to the inhibitory effect on the production of cellular cytokines and arachidonic acid metabolites. In patients with COPD it traditionally improves airway patency.

Indications
This is indicated in-

  • Productive cough.
  • Acute and chronic inflammatory disorders of upper and lower respiratory tracts associated with viscid mucus including acute and chronic bronchitis.
  • Inflammatory disease of rhinopharyngeal tract (laryngitis, pharyngitis, sinusitis and rhinitis) associated with viscid mucus.
  • Asthmatic bronchitis bronchial asthma with thick expectoration.
  • Chronic pneumonia etc.

Dosage & Administration
Average daily dose (preferably after meal):

  • 2-5 years: 5 ml (1/2 teaspoonful) 2-3 times a day.
  • 5-10 years: 5 mi (1 teaspoonful) 2-3 times a day.
  • 10 years and adults: 10 ml (2 teaspoonful) 3 times a day.

Contraindications
Contraindicated in known hypersensitivity to Mucovan (Ambroxol) or Bromhexine.

Precautions & Warnings
Mucovan (Ambroxol) should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.

Side Effects
Gastrointestinal side effects like epigastric pain, stomach overfill feeling may occur occasionally. Rarely allergic responses such as eruption, urticaria or angioneurotic edema have been reported.

Pregnancy & Lactation
Teratogenic and fetal toxicity studies have shown no harmful effect of Mucovan (Ambroxol). However, it is advised not to use it in pregnancy, especially during the 1st trimester Safety during lactation, has not been established yet.

Interaction
Mucovan (Ambroxol) should not be taken simultaneously with antitussives (e.g. Codeine) because phlegm, which has been liquefied by Mucovan (Ambroxol) might not be expectorated.

Storage
Store below 30°C, protect from light and moisture. Keep out of reach of children.

Packaging
Each PET bottle contains 100 ml syrup and a measuring cup.

Mucovan Syrup
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