COMPOSITION
Each tablet contains Riboflavine USP 5 mg.
PHARMACOLOGY
Ribomin (Riboflavin or vitamin B2) is an easily absorbed, water-soluble micronutrient with a key role in maintaining human health. Like the other B vitamins, it supports energy production by aiding in the metabolising of fats, carbohydrates, and proteins. Vitamin B2 is also required for red blood cell formation and respiration, antibody production, and for regulating human growth and reproduction. It is essential for healthy skin, nails, hair growth and general good health, including regulating thyroid activity. Riboflavin also helps in the prevention or treatment of many types of eye disorders, including some cases of cataracts.
Binds to riboflavin hydrogenase, riboflavin kinase, and riboflavin synthase. Riboflavin is the precursor of flavin mononucleotide (FMN, riboflavin monophosphate) and flavin adenine dinucleotide (FAD). The antioxidant activity of riboflavin is principally derived from its role as a precursor of FAD and the role of this cofactor in the production of the antioxidant reduced glutathione. Reduced glutathione is the cofactor of the selenium-containing glutathione peroxidases among other things. The glutathione peroxidases are major antioxidant enzymes. Reduced glutathione is generated by the FAD-containing enzyme glutathione reductase.
INDICATION
Ribomin (Riboflavin or vitamin B2) is used to prevent and to treat deficiencies of vitamin B2 such as cheilosis, angular stomatitis, glossitis, keratitis, seborrhoeic dermatitis.
DOSE AND ADMINISTRATION
5-10 mg tablet 2-3 times daily.
CONTRAINDICATION
None reported.
WARNING & PRECAUTION
Riboflavin is non-toxic. No warnings or precautions have been established.
SIDE EFFECTS
Riboflavin is likely safe for most people. In some people, Riboflavin can cause the urine to turn a yellow- orange color. When taken in high doses, Riboflavin might cause diarrhea, an increase in urine, and other side effects.
USE IN PREGNANCY AND LACTATION
Ribomin (Riboflavine) is generally regarded as being safe during pregnancy and breastfeeding.
DRUG INTERACTION
Tricyclic antidepressants, phenothiazines, probenecid antimalarial drugs and alcohol decrease effects. Tobacco decreases absorption.
STORAGE
Store in a cool & dry place below 30º C. Protect from light and moisture. Keep out of reach of children.
PACKING
Ribomin Tablet: Each box containing 50 x10’s tablets in blister pack
