Tium Injection

Tium Injection
Tiemonium Methylsulphate INN 5 mg.

Each 2 ml sterile solution contains Tiemonium Methylsulphate INN 5 mg.

Tium (Tiemonium Methylsulphate) is an antispasmodic drug. It reduces the muscle spasm of the intestine, biliary system, bladder and uterus. Tium is readily absorbed from the gastrointestinal tract. It is rapidly cleared from the blood and is distributed throughout the body. It is incompletely metabolized in the liver and is excreted in the urine as unchanged drug and metabolites. A half-life of about 4 hours has been reported.

Tium (Tiemonium Methylsulfate) is indicated for
• Visceral pain
• Muscle spasm of the intestine, biliary system, bladder & uterus
• Pain in gastrointestinal and biliary diseases e.g. hepatocolic, colitis, gastric & duodenal ulcer & acute pain
• Gynecology and renal colic

Dosage & Administration
Recommended injectable dose is one or two Tium (Tiemonium Methylsulphate) Injection three times daily through intravenous route slowly or intramuscular route.
Or recommended by registered physician.

Tiemonium Methylsulphate should not be used in Glaucoma (acute pain of eyeball with vision disturbance), difficulty to urinate (disorders of prostate or bladder), tachycardia, myocardial infarction, pyloric stenosis and acute edema of the lung.

Caution should be taken in case of chronic bronchitis, coronary insufficiency, ambient hyperthermia, cardiac disorders, thyroid disorders, serious renal & hepatic insufficiency.

Side Effects
Side effects include dryness of mouth with difficulty in swallowing & thirst, difficulty with micturition & constipation, risk of hypotension & tachycardia, occasional retention of urine in excessive or overdoses.

Use in Pregnancy & Lactation
This drug should never be used without specific instruction of the physician during pregnancy & breastfeeding.

Drug Interaction
The effects of Tiemonium Methylsulphate may be enhanced by the concomitant use of other drugs with antimuscarinic properties such as- amantadine, some antihistamines, phenothiazine, antipsychotics and antidepressants.

There is not available data regarding the overdose of Tiemonium Methylsulphate.

Store below 30°C, protect from light & moisture. Keep out of the reach of children.

Tium Injection: Each box contains 10 ampoules of 2 ml sterile solution of Tiemonium Methylsulphate.

Tium Injection
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