Alerjess
Chlorpheniramine Maleate BP
Composition
Each 5 ml syrup contains 2 mg Chlorpheniramine Maleate BP.
Pharmacology
Chlorpheniramine Maleate is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine Chlorpheniramine Maleate exerts its effects by blocking it-receptor competitively.
Indications
Chlorpheniramine Maleate is indicated in the following indications:
- Sensitivity reactions
- Angioneurotic edema
- Vasomotor rhinitis
- Cough
- Common cold
- Motion sickness and
- Other allergic conditions.
Dosage & Administration
Adult-Usual adult dose is 4 mg every 4-6 hours maximum 24 mg daily-
Child:
- 6-12 years: 2 mg every 4-6 hours maximum 12 mg daily.
- 2-5 years: 1mg every 4 hours maximum & 6 mg daily.
- 1-2 years: 1 mg twice daily.
Below 1 year the Chlorpheniramine Maleate is not recommended.
Interaction
Chlorpheniramine maleate has been reported to be incompatible with calcium chloride kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium and meglumine adipiodone.
Contraindications
Chlorpheniramine is contraindicated in patients hypersensitive to this agent. in newborn or premature infants.
Precautions & Warnings
Chlorpheniramine should be used with caution in patients with glaucoma and prostatic hypertrophy. During therapy with chlorpheniramine, caution should be taken in driving vehicles and operating machinery.
Side Effects
Chlorpheniramine is well-tolerated, but sometimes drowsiness, dizziness, muscular weakness, and gastrointestinal upset may occur.
Pregnancy & Lactation
This drug should not be used in lactating mother and in pregnancy especially during the first trimester of pregnancy.
Overdose
CNS depression (including sedation apnea: CV collapse), CNS stimulation (including insomnia hallucination tremors convulsions) tinnitus, blurred vision, dizziness, ataxia, hypotension Stimulation and atropine-like signs and symptoms (including try mouth, fixed dilated pupils flushing hyperthermia of symptoms are more likely in children.
Storage
Store below 30°C, protect from light and moisture. Keep out of reach of children.
Packaging
Each Box contains 500 tablets in blister pack.
